We asked Jason Miller, DACM, Chief Formulator of Green Earth Medicinals, to explain why he includes Prickly Ash (Zanthoxylum clava-herculis) in his CBD botanical formulations.
 

Prickly Ash is a tree native to the Americas with diffusive stimulant properties. It naturally contains alkyl amides that are responsible for the tingling and saliva producing sensations associated with oral consumption of echinacea or spilanthes, and they have been identified as cannabinoid receptor activators.

As a diffusive stimulant that increases secretions, prickly ash is one of several medicinal plants known to contain a group of chemical compounds called “alkyl amides.” This plant is a synergist with hemp extract. We include it in our CBD ORAL | Buccal Spray and CBD ORAL | Sleep Spray to facilitate absorption of CBD and enhance the formula’s effect on the ECS (Endocannabinoid System).

At Green Earth Medicinals, we combine full-spectrum CBD with other botanicals to create uniquely effective products. To learn more about why we do this, please watch this educational video from our Understanding CBD video series:

Citations:
1. Gertsch, J. (2010). Phytocannabinoids beyond the Cannabis plant – do they exist? British Journal of Pharmacol. 2010 Jun; 160(3): 523–529.
2. Spelman, K. (2015). Keeping It Together: The Other Compounds in Cannabis and the Benefits of Whole-herb Use. Integr Med (Encinitas). 2015 Jun; 14(3): 18–22.